An annealing mutation operator in the genetic algorithms for RNA folding

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An annealing mutation operator in the genetic algorithms for RNA folding

An annealing mutation operator in the genetic algorithms (GA) for RNA folding on a MasPar MP-2 has been designed. The mutation probability descends along a hyperbola with respect to the size of the secondary structure, hence the total number of mutations at each generation drops linearly. Especially for long sequences with thousands of nucleotides as opposed to hundreds of nucleotides, the new ...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 1996

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/12.3.171